APAP therapy does not improve impaired sleep quality and sympatho-vagal balance: a randomized trial in patients with obstructive sleep apnea and systolic heart …

J Spiesshoefer, J Aries, A Giannoni, M Emdin, H Fox… - Sleep and …, 2020 - Springer
Purpose In heart failure with reduced ejection fraction (HFrEF), the effects of automatic
positive airway pressure therapy (APAP) for obstructive sleep apnea (OSA) on sleep quality
and sympatho-vagal balance (SVB) are unknown. Methods In this randomized controlled
trial (6 months of APAP vs. nasal strips as control), sleep quality and SVB in patients with
HFrEF and OSA were monitored. The distinction was made between different breathing
conditions (5-min segments of OSA or normal breathing [NB] during stable N2 sleep) at …

P4520 APAP therapy does not improve impaired sleep quality and sympatho-vagal balance: a randomized trial in patients with obstructive sleep apnea and systolic …

J Spiesshoefer, JA Aries, AG Giannoni… - European Heart …, 2019 - academic.oup.com
Introduction and purpose In heart failure with reduced ejection fraction (HFrEF), the effects of
automatic positive airway pressure therapy (APAP) for obstructive sleep apnea (OSA) on
sleep quality and sympatho-vagal balance (SVB) are unknown. Methods In this randomized
controlled trial, sleep quality and SVB in patients with HFrEF and OSA were monitored
noninvasively across different breathing conditions (5-minute segments of OSA or normal
breathing [NB]) during stable N2 sleep) at baseline (T0), during APAP initiation (T1) and …
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